Friday, June 27, 2025

Stand Alone Diets: Each One Results In Ripped

 


⚡️ 1. High-Carbohydrate Diet (90%+ CHO)

Main Pathway: Glycolysis

  • Fuel Source: Glucose
  • Storage Form: Glycogen (liver and muscle)
  • Hormonal Shift:
    • Insulin
    • Glucagon
    • Cortisol
  • Energy Mode: Fast, anaerobic and aerobic
  • Metabolic Traits:
    • Low fat oxidation
    • Minimal ketone production
    • Elevated blood glucose turnover
  • Hormone Parallel:
    • Low FGF-21 activity (FGF21 suppressed in high glucose states)
    • High insulin sensitivity initially, but risk of insulin resistance long-term if unchecked.

🧬 2. High-Protein Diet (Predominantly Protein)

Main Pathway: Gluconeogenesis (GNG)

  • Fuel Source: Amino acids → Glucose
  • Storage Form: Glucose (via hepatic conversion)
  • Hormonal Shift:
    • Glucagon
    • Moderate ↑ Insulin
    • Cortisol (if protein intake is extreme or carb-depleted)
  • Energy Mode: Slower, protein-derived ATP production
  • Metabolic Traits:
    • GNG is slower than glycolysis
    • Not optimal for fast performance
    • Risk of ammonia build-up (urea cycle burden)
  • Hormone Parallel:
    • FGF21 moderately elevated, especially in carb-restricted, high-protein settings.
    • Promotes energy expenditure and fat oxidation supportively.

🔥 3. High-Fat Diet (Predominantly Fat – Keto/Carnivore)

Main Pathway: Ketosis

  • Fuel Source: Fatty acids → Ketone bodies (β-HB, acetoacetate)
  • Storage Form: Triglycerides
  • Hormonal Shift:
    • Insulin
    • Glucagon
    • FGF21 —> Key ketogenic adaptation hormone
    • Adiponectin
  • Energy Mode: Sustained, clean-burning, mitochondrial-efficient
  • Metabolic Traits:
    • Appetite suppression
    • Muscle preservation (especially in presence of ketones)
    • Cognitive stability and endurance
  • Hormone Parallel:
    • High FGF21 levels, which promotes fat oxidation, mitochondrial biogenesis, and insulin sensitivity.
    • FGF21 is a hallmark of fasting and ketogenic states, acting like a master switch for adaptive metabolism.

⚙️ Summary Comparison Table:

Macronutrient Focus Metabolic Pathway Primary Hormone(s) FGF21 Response Energy Mode
High-Carb (90% CHO) Glycolysis ↑ Insulin ↓ FGF21 Fast, glycolytic
High-Protein Gluconeogenesis (GNG) ↑ Glucagon, Cortisol ↑ FGF21 (mod) Moderate, stress-adapted
High-Fat (Keto) Ketosis ↑ FGF21, Glucagon ↑↑ FGF21 Efficient, endurance


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